MARIE-ÈVE PAQUET, CENTRAL CANADA REPRESENTATIVE

Centre de recherche Institut Universitaire en Santé Mentale de Québec

 I was trained as an undergraduate in biochemistry at l’Université Laval in Québec city and through several summer projects I developed an interest for immunology. I pursued my graduate studies in the department of immunology at the University of Toronto where I focussed on the molecular aspects of antigen processing. After several years at U of Toronto, I joined the laboratory of Hidde Ploegh as a post-doctoral fellow at the Whitehead Institute (MIT) to develop an expertise on in vivo gene transfer, viral evasion and the ER stress response. It is with a strong background in immunology, virology and molecular biology that I joined the IUSMQ (Université Laval) in 2008 to start a new core facility that develops genetically-encoded molecular tools for optical imaging and photointervention in vivo. Our group is now part of the Canadian Neurophotonics Platform funded by Brain Canada and, under my leadership, has become Canada’s frontrunner in the development and production of viral vectors for optogenetics. We now provide adeno-associated viruses (AAV), lentiviruses, retroviruses and adenoviruses to numerous North American labs and have established partnerships with major optogenetics tools developers such as Janelia Farm scientists, Karl Deisseroth (Stanford U.) ,Ed Boyden (MIT) and Robert Campbell (UofA).

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